Publications

Scientific Output

Explore our scientific publications and latest research findings

Publications shown: 38

2026

The azole-resistance phenotype of a Nakaseomyces glabratus clinical strain encoding a wild-type PDR1 allele involves the efflux pumps Aus1 and Pdh1 and Cyb5, an alternative reductase required for ergosterol biosynthesis

Pinheiro MJ · Parker JE · Ferreira MT · Fernandes F · Mira NP

Microbiology Spectrum · 2026DOI →

2025

Evaluation of antibacterial properties of Lactobacillus acidophilus and Lactobacillus gasseri on enterotoxigenic Escherichia coli associated with porcine post-weaning diarrhea (PWD) using Galleria mellonella model

Araújo D · Silva AR · Silva S · Mira NP · Almeida C · Castro J

The Microbe · 2025DOI →

Vapor phase of white thyme essential oil: effect on Candida albicans and preservation of Lactobacillus species in the context of vulvovaginal candidiasis

Fernandes L · Silva I · Araújo D · Costa R · Silva S · Mira NP · Costa-de-Oliveira S · Henriques M · Rodrigues ME

BMC Complementary Medicine and Therapies · 2025DOI →

The transcription factor CgHaa1 plays a role in virulence of the pathogenic yeast Candida glabrata

Salazar SB · Pedro NA · Silva S · Mil-Homens D · Pimenta A · Wlodarczyk M · Szwed-Georgiou A · Sasamoto K · Chibana H · Michlewska S · Rudnicka K · Fialho A · Mira NP

FEMS Yeast Research · 2025DOI →

2024

Methods for studying microbial acid stress responses: from molecules to populations

Atasoy M · Bartkova S · Çetecioğlu-Gürol Z · Mira NP · O'Byrne C · Pérez-Rodríguez F · Possas A · Scheler O · Sedláková-Kaduková J · Sinčák M · Steiger M · Ziv C · Lund PA

FEMS Microbiology Reviews · 2024DOI →

On the potential role of naturally occurring carboxylic organic acids as anti-infective agents: opportunities and challenges

Mira NP · Marshall R · Pinheiro MJ · Dieckmann R · Al Dahouk SA · Skroza N · Rudnicka K · Lund PA · De Biase D

International Journal of Infectious Diseases · 2024DOI →

A molecular view on the interference established between vaginal Lactobacilli and pathogenic Candida species: Challenges and opportunities for the development of new therapies

Pedro NA · Mira NP

Microbiological Research · 2024DOI →

2023

Insights into the transcriptional regulation of poorly characterized alcohol acetyltransferase-encoding genes (HgAATs) shed light into the production of acetate esters in the wine yeast Hanseniaspora guilliermondii

Seixas I · Santos D · Vasconcelos I · Mira NP · Mendes-Ferreira A

FEMS Yeast Research · 2023DOI →

A Genome-Wide Phenotypic Analysis of Saccharomyces cerevisiae’s Adaptive Response and Tolerance to Chitosan in Conditions Relevant for Winemaking

Lage P · Coelho BB · Mira NP · Mendes-Ferreira A

Fermentation · 2023DOI →

2022

Cyclam-based iron(III) and copper(II) complexes: synthesis, characterization and application as antifungal agents

Almada S · Maia LB · Waerenborgh JC · Vieira BJC · Mira NP · Silva ER · Cerqueira F · Pinto E · Alves LG

New Journal of Chemistry · 2022DOI →

Disclosing azole resistance mechanisms in resistant C. glabrata strains encoding wild-type or gain-of-function CgPDR1 alleles through comparative genomics and transcriptomics

Salazar SB · Pinheiro MJ · Sotti-Novais D · Soares AR · Lopes MM · Ferreira T · Rodrigues V · Fernandes F · Mira NP

G3: Genes, Genomes, Genetics · 2022DOI →

Integrated perspective on microbe-based production of itaconic acid: From metabolic and strain engineering to upstream and downstream strategies

Nascimento MF · Marques N · Correia J · Faria NT · Mira NP · Ferreira FC

Process Biochemistry · 2022DOI →

2021

Implementation of Synthetic Pathways to Foster Microbe-Based Production of Non-Naturally Occurring Carboxylic Acids and Derivatives

Vila-Santa A · Mendes FC · Ferreira FC · Prather KLJ · Mira NP

Journal of Fungi · 2021DOI →

Bioactive Coatings with Ag-Camphorimine Complexes to Prevent Surface Colonization by the Pathogenic Yeast Candida albicans

Pinheiro MJ · Costa JP · Marques F · Mira NP · Carvalho MFNN · Alves MM

Antibiotics · 2021DOI →

Prospecting Biochemical Pathways to Implement Microbe-Based Production of the New-to-Nature Platform Chemical Levulinic Acid

Vila-Santa A · Islam MA · Ferreira FC · Prather KLJ · Mira NP

ACS Synthetic Biology · 2021DOI →

Genome sequencing, annotation and exploration of the SO₂-tolerant non-conventional yeast Saccharomycodes ludwigii

Tavares MJ · Güldener U · Mendes-Ferreira A · Mira NP

BMC Genomics · 2021DOI →

2020

Understanding How Microorganisms Respond to Acid pH Is Central to Their Control and Successful Exploitation

Lund PA · De Biase D · Liran O · Scheler O · Mira NP · Cetecioglu Z · Noriega Fernández E · Bover-Cid S · Hall R · Sauer M · O’Byrne C

Frontiers in Microbiology · 2020DOI →

Effect of progesterone on Candida albicans biofilm formation under acidic conditions: A transcriptomic analysis

Gonçalves B · Bernardo R · Wang C · Schröder MS · Pedro NA · Butler G · Azeredo J · Henriques M · Mira NP · Silva S

International Journal of Medical Microbiology · 2020DOI →

MOMO - multi-objective metabolic mixed integer optimization: application to yeast strain engineering

Andrade R · Doostmohammadi M · Santos JL · Sagot MF · Mira NP · Vinga S

BMC Bioinformatics · 2020DOI →

Metabolic engineering of an acid-tolerant yeast strain Pichia kudriavzevii for itaconic acid production

Sun W · Vila-Santa A · Liu N · Prozorov T · Xie D · Faria NT · Ferreira FC · Mira NP · Shao Z

Metabolic Engineering Communications · 2020DOI →

An Overview on Conventional and Non-Conventional Therapeutic Approaches for the Treatment of Candidiasis and Underlying Resistance Mechanisms in Clinical Strains

Salazar SB · Simões RS · Pedro NA · Pinheiro MJ · Carvalho MFNN · Mira NP

Journal of Fungi · 2020DOI →

Metabolic specialization in itaconic acid production: a tale of two fungi

Wierckx N · Agrimi G · Lübeck PS · Steiger MG · Mira NP · Punt PJ

Current Opinion in Biotechnology · 2020DOI →

2019

Characterizing the Potential of the Non-Conventional Yeast Saccharomycodes ludwigii UTAD17 in Winemaking

Esteves M · Barbosa C · Vasconcelos I · Tavares MJ · Mendes-Faia A · Mira NP · Mendes-Ferreira A

Microorganisms · 2019DOI →

Transcriptomic and chemogenomic analyses unveil the essential role of Com2-regulon in response and tolerance of Saccharomyces cerevisiae to stress induced by sulfur dioxide

Lage P · Sampaio-Marques B · Ludovico P · Mira NP · Mendes-Ferreira A

Microbial Cell · 2019DOI →

Study of the activity of Punica granatum-mediated silver nanoparticles against Candida albicans and Candida glabrata, alone or in combination with azoles or polyenes

Souza JAS · Alves MM · Barbosa DB · Lopes MM · Pinto E · Figueiral MH · Delbem ACB · Mira NP

Medical Mycology · 2019DOI →

Antimicrobial Activity of Silver Camphorimine Complexes against Candida Strains

Costa JP · Pinheiro MJ · Sousa SA · Botelho do Rego AM · Marques F · Oliveira MC · Leitão JH · Mira NP · Carvalho MFNN

Antibiotics · 2019DOI →

Effect of Acetic Acid and Lactic Acid at Low pH in Growth and Azole Resistance of Candida albicans and Candida glabrata

Lourenço A · Pedro NA · Salazar SB · Mira NP

Frontiers in Microbiology · 2019DOI →

A Transcriptomics Approach To Unveiling the Mechanisms of In Vitro Evolution towards Fluconazole Resistance of a Candida glabrata Clinical Isolate

Cavalheiro M · Costa C · Silva-Dias A · Miranda IM · Wang C · Pais P · Pinto SN · Mil-Homens D · Sato-Okamoto M · Takahashi-Nakaguchi A · Silva RM · Mira NP · Fialho AM · Chibana H · Rodrigues AG · Butler G · Teixeira MC

Antimicrobial Agents and Chemotherapy · 2019DOI →

2018

Genome sequence of the non-conventional wine yeast Hanseniaspora guilliermondii UTAD222 unveils relevant traits of this species and of the Hanseniaspora genus in the context of wine fermentation

Seixas I · Barbosa C · Mendes-Faia A · Güldener U · Tenreiro R · Mendes-Ferreira A · Mira NP

DNA Research · 2018DOI →

Genome Sequence of the Wine Yeast Saccharomycodes ludwigii UTAD17

Tavares MJ · Güldener U · Esteves M · Mendes-Faia A · Mendes-Ferreira A · Mira NP

Microbiology Resource Announcements · 2018DOI →

In silico, in vitro and antifungal activity of the surface layers formed on zinc during this biomaterial degradation

Alves MM · Marques LM · Nogueira I · Santos CF · Salazar SB · Eugénio S · Mira NP · Montemor MF

Applied Surface Science · 2018DOI →

Potential anti-cancer and anti-Candida activity of Zn-derived foams

Marques LM · Alves MM · Eugénio S · Salazar SB · Pedro NA · Grenho L · Mira NP · Fernandes MH · Montemor MF

Journal of Materials Chemistry B · 2018DOI →

Microstructured ZnO-rod like coating prevents biofilm formation prompted by pathogenic Candida spp.

Alves MM · Cunha DV · Santos CF · Mira NP · Montemor MF

Ceramics International · 2018DOI →

2017

The multidrug resistance transporters CgTpo1_1 and CgTpo1_2 play a role in virulence and biofilm formation in the human pathogen Candida glabrata

Santos R · Costa C · Mil-Homens D · Romão D · de Carvalho CCCR · Pais P · Mira NP · Fialho AM · Teixeira MC

Cellular Microbiology · 2017DOI →

Mechanistic insights underlying tolerance to acetic acid stress in vaginal Candida glabrata isolates

Cunha D, Salazar SB, Lopes MM, Mira NP.

Frontiers in Microbiology 8:259.DOI →

The CgHaa1-regulon mediates response and tolerance to acetic acid stress in the human pathogen Candida glabrata

Bernardo R, Cunha DV, Wang C, Pereira L, Silva S, Salazar SB, Schroeder MS, Okamoto M, Takahashi-Nakaguchi A, Chibana H, Aoyoama T, Sá-Correia I, Azeredo J, Butler G, Mira NP.

G3: Genes, Genomes and Genetics 7:1-18.DOI →

2015

Genomic expression program of Saccharomyces cerevisiae along a mixed-culture wine fermentation with Hanseniaspora guilliermondii

Barbosa C · Mendes-Faia A · Lage P · Mira NP · Mendes-Ferreira A

Microbial Cell Factories · 2015DOI →

2014

Candida glabrata drug: H+ antiporter CgTpo3 (ORF CAGL0I10384g): role in azole drug resistance and polyamine homeostasis

Costa C · Nunes J · Henriques A · Mira NP · Nakayama H · Chibana H · Teixeira MC

Journal of Antimicrobial Chemotherapy · 2014DOI →